Mouse Evc2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Evc2
Locus ID	68525
Kit Components	GA207844G1, Evc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207844G2, Evc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207844G3, Evc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145920
Synonyms	1110017L09Rik; Lbn; limbin
Summary	Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (PubMed:21356043, PubMed:24582806). Plays a critical role in bone formation and skeletal development (PubMed:21356043). May be involved in early embryonic morphogenesis (PubMed:21356043).[UniProtKB/Swiss-Prot Function]

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