Mouse Ccdc88c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccdc88c
Locus ID	68339
Kit Components	GA207783G1, Ccdc88c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207783G2, Ccdc88c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207783G3, Ccdc88c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026681, NM_001362342
Synonyms	0610010D24Rik; AV000935; AW324073; Daple; mKIAA1509
Summary	Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization (PubMed:14750955). May also activate the JNK signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]

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