Mouse Smc6 activation kit by CRISPRa
CAT#: GA207219
Smc6 CRISPRa kit - CRISPR gene activation of mouse structural maintenance of chromosomes 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Smc6 |
Locus ID | 67241 |
Kit Components | GA207219G1, Smc6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207219G2, Smc6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207219G3, Smc6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001324476, NM_025695, NM_001361252 |
Synonyms | 2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; mKIAA4103; SMC-6; Smc6l1 |
Summary | Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN516300 | Smc6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |