Mouse Dram2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dram2
Locus ID	67171
Kit Components	GA207182G1, Dram2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207182G2, Dram2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207182G3, Dram2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001025582, NM_001286986, NM_001286987, NM_026013
Synonyms	2010305N14Rik; 2610318G18Rik; AI647667; Tmem77
Summary	Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1.[UniProtKB/Swiss-Prot Function]

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