Mouse Nkap activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkap
Locus ID	67050
Kit Components	GA207109G1, Nkap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207109G2, Nkap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207109G3, Nkap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_025937
Synonyms	2610020O08Rik; AA987160; AI849147; AL024236
Summary	Acts as a transcriptional repressor. Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development. Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter (By similarity).[UniProtKB/Swiss-Prot Function]

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