Mouse Rbm7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rbm7
Locus ID	67010
Kit Components	GA207081G1, Rbm7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207081G2, Rbm7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207081G3, Rbm7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001326355, NM_001326356, NM_144948, NR_037589, NR_136937
Synonyms	1200007M24Rik; 1500011D06Rik; AU041934; AW554393
Summary	Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. Possible involved in germ cell RNA processing and meiosis.[UniProtKB/Swiss-Prot Function]

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