Mouse Edem3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Edem3
Locus ID	66967
Kit Components	GA207055G1, Edem3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207055G2, Edem3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207055G3, Edem3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039644, NM_001311165, NM_001311166
Synonyms	2310050N11Rik
Summary	Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity.[UniProtKB/Swiss-Prot Function]

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