Mouse Atg10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atg10
Locus ID	66795
Kit Components	GA206959G1, Atg10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206959G2, Atg10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206959G3, Atg10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_025770
Synonyms	5330424L23Rik; 5430428K15Rik; Agp10; AI852123; APG10; Apg10l; Apg10p; Atg10l
Summary	E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Plays a role in adenovirus-mediated cell lysis.[UniProtKB/Swiss-Prot Function]

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