Mouse Hspbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hspbp1
Locus ID	66245
Kit Components	GA206660G1, Hspbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206660G2, Hspbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206660G3, Hspbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_024172, NM_001360629
Synonyms	1500019G21Rik
Summary	Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of target proteins (By similarity).[UniProtKB/Swiss-Prot Function]

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