Mouse Osbpl1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osbpl1a
Locus ID	64291
Kit Components	GA206450G1, Osbpl1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206450G2, Osbpl1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206450G3, Osbpl1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252489, NM_001252490, NM_001252491, NM_001252492, NM_001252493, NM_207530, NR_045524, NM_020573
Synonyms	G430090F17Rik; Gm753; ORP-1; Osbpl1b
Summary	Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A. Binds 25-hydroxycholesterol and cholesterol.[UniProtKB/Swiss-Prot Function]

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