Mouse Apba3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Apba3
Locus ID	57267
Kit Components	GA206147G1, Apba3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206147G2, Apba3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206147G3, Apba3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018758
Synonyms	AW208791; lin-10; Mint-3; mint3; X11gamma
Summary	May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN (By similarity).[UniProtKB/Swiss-Prot Function]

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