Mouse Trpc4ap activation kit by CRISPRa
CAT#: GA205951
Trpc4ap CRISPRa kit - CRISPR gene activation of mouse transient receptor potential cation channel, subfamily C, member 4 associated protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Trpc4ap |
Locus ID | 56407 |
Kit Components | GA205951G1, Trpc4ap gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205951G2, Trpc4ap gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205951G3, Trpc4ap gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001163452, NM_019828 |
Synonyms | 4833429F06Rik; D2Ertd113e; mFLJ00177; Trrp4ap; truss |
Summary | Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC (By similarity). Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN518293 | Trpc4ap - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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