Mouse Pdzrn3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdzrn3
Locus ID	55983
Kit Components	GA205794G1, Pdzrn3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205794G2, Pdzrn3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205794G3, Pdzrn3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_018884
Synonyms	1110020C07Rik; AI429718; AL023082; LNX3; SEMACAP3; Semcap3
Summary	E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.[UniProtKB/Swiss-Prot Function]

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