Mouse Nphs1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nphs1
Locus ID	54631
Kit Components	GA205742G1, Nphs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205742G2, Nphs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205742G3, Nphs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019459
Synonyms	nephrin; NephrinB
Summary	Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.[UniProtKB/Swiss-Prot Function]

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