Mouse Ccrl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccrl2
Locus ID	54199
Kit Components	GA205663G1, Ccrl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205663G2, Ccrl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205663G3, Ccrl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302376, NM_001302377, NM_017466
Synonyms	1810047I05Rik; Ackr5; CCR11; Cmkbr1l2; E01; L-CCR
Summary	Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity).[UniProtKB/Swiss-Prot Function]

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