Mouse Slc46a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc46a1
Locus ID	52466
Kit Components	GA205477G1, Slc46a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205477G2, Slc46a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205477G3, Slc46a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026740
Synonyms	1110002C08Rik; D11Ertd18e; HCP1; Pcft
Summary	Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.[UniProtKB/Swiss-Prot Function]

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