Mouse Cdk2ap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdk2ap2
Locus ID	52004
Kit Components	GA205435G1, Cdk2ap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205435G2, Cdk2ap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205435G3, Cdk2ap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026373
Synonyms	5830466O21Rik; D19Ertd144e; Doc-1r
Summary	Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs (PubMed:22548356). Regulates microtubule organization of metaphase II oocytes (PubMed:12944431). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (By similarity).[UniProtKB/Swiss-Prot Function]

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