Mouse Atg13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atg13
Locus ID	51897
Kit Components	GA205430G1, Atg13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205430G2, Atg13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205430G3, Atg13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145528, NM_001355416, NM_001355417, NM_001355418, NM_001355419, NM_001355420, NM_001355421
Synonyms	1110053A20Rik; D2Ertd391e; Harbi1
Summary	Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.[UniProtKB/Swiss-Prot Function]

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