Mouse Il27ra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il27ra
Locus ID	50931
Kit Components	GA205405G1, Il27ra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205405G2, Il27ra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205405G3, Il27ra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_016671
Synonyms	CRL1; IL-27R; Tccr; WSX-1; Wsx1; zcytor1
Summary	Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.[UniProtKB/Swiss-Prot Function]

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