Mouse Nasp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nasp
Locus ID	50927
Kit Components	GA205402G1, Nasp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205402G2, Nasp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205402G3, Nasp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081475, NM_001284229, NM_016777
Synonyms	5033430J04Rik; AI131596; AI317140; D4Ertd767e; Epcs32; Nasp-T
Summary	Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and linker H1 histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.[UniProtKB/Swiss-Prot Function]

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