Mouse Mapk6 activation kit by CRISPRa
CAT#: GA205354
Mapk6 CRISPRa kit - CRISPR gene activation of mouse mitogen-activated protein kinase 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Mapk6 |
Locus ID | 50772 |
Kit Components | GA205354G1, Mapk6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205354G2, Mapk6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205354G3, Mapk6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_015806, NM_027418 |
Synonyms | 2610021I23Rik; D130053K17Rik; Erk3; Mapk4; Mapk63; Prkm4; Prkm6 |
Summary | Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN509766 | Mapk6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |