Mouse Siva1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Siva1
Locus ID	30954
Kit Components	GA205305G1, Siva1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205305G2, Siva1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205305G3, Siva1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001161737, NM_013929
Synonyms	CD27bp; Siva
Summary	Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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