Mouse Synj2bp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Synj2bp
Locus ID	24071
Kit Components	GA204889G1, Synj2bp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204889G2, Synj2bp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204889G3, Synj2bp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001309814, NM_025292, NR_132136, NR_132142
Synonyms	AA409442; ActRIP4; ARIP2; D12Wsu118e; OMP25
Summary	Isoform 1 regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction. Isoform 2 and isoform 3 show a stimulatory affect on activin-induced signal transduction and enhance activin type 2 expression at the cell surface.[UniProtKB/Swiss-Prot Function]

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