Mouse Hax1 activation kit by CRISPRa
CAT#: GA204806
Hax1 CRISPRa kit - CRISPR gene activation of mouse HCLS1 associated X-1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Hax1 |
Locus ID | 23897 |
Kit Components | GA204806G1, Hax1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204806G2, Hax1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204806G3, Hax1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001282032, NM_001310681, NM_011826 |
Synonyms | HAX-1; Hs1bp1; HSP1BP-1; mHAX-1s; SIG-111; Silg111 |
Summary | Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN507585 | Hax1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |