Mouse Grem1 activation kit by CRISPRa

CAT#: GA204803

Grem1 CRISPRa kit - CRISPR gene activation of mouse gremlin 1, DAN family BMP antagonist



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
Rabbit Polyclonal Anti-Grem1 Antibody
    • 50 ug

CNY 5,200.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Grem1
Locus ID 23892
Kit Components

GA204803G1, Grem1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204803G2, Grem1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204803G3, Grem1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_011824
Synonyms Cktsf1b1; Drm; Grem; ld
Summary Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop (PubMed:12808456, PubMed:15201225). Down-regulates the BMP4 signaling in a dose-dependent manner (PubMed:15133038). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (By similarity). Acts as inhibitor of monocyte chemotaxis (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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