Mouse Dmtf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dmtf1
Locus ID	23857
Kit Components	GA204785G1, Dmtf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204785G2, Dmtf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204785G3, Dmtf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001110327, NM_011806, NR_152858, NR_152859, NR_152860, NR_152861
Synonyms	Dimp; Dmp1
Summary	Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest. May also cooperate with MYB to activate transcription of the ANPEP gene. Binds to the consensus sequence 5'-CCCG[GT]ATGT-3'.[UniProtKB/Swiss-Prot Function]

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