Mouse Tnfaip1 activation kit by CRISPRa

CAT#: GA204386

Tnfaip1 CRISPRa kit - CRISPR gene activation of mouse tumor necrosis factor, alpha-induced protein 1 (endothelial)



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Tnfaip1
Locus ID 21927
Kit Components

GA204386G1, Tnfaip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204386G2, Tnfaip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204386G3, Tnfaip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001159392, NM_009395
Synonyms Bacurd2; Edp-1; Edp1; Tnfip1
Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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