Mouse Timm44 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Timm44
Locus ID	21856
Kit Components	GA204354G1, Timm44 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204354G2, Timm44 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204354G3, Timm44 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011592
Synonyms	0710005E20Rik; D8Ertd118e; Mimt44; Tim44
Summary	Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.[UniProtKB/Swiss-Prot Function]

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