Mouse Stxbp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Stxbp2
Locus ID	20911
Kit Components	GA204157G1, Stxbp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204157G2, Stxbp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204157G3, Stxbp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011503, NM_001357168
Synonyms	C79054; Munc-18-2; Munc-18b; Munc18b; muSec1; Sxtbp2; Sxtp2; Unc18-2; Unc18b
Summary	Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity).[UniProtKB/Swiss-Prot Function]

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