Mouse Stxbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Stxbp1
Locus ID	20910
Kit Components	GA204156G1, Stxbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204156G2, Stxbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204156G3, Stxbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113569, NM_009295
Synonyms	AI317162; AI326233; MMS10-G; Ms10g; Munc-18a; Munc18-1; N-sec1; nsec1; Rb-sec1; Sxtbp1
Summary	Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions (By similarity).[UniProtKB/Swiss-Prot Function]

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