Mouse Sos1 activation kit by CRISPRa
CAT#: GA204023
Sos1 CRISPRa kit - CRISPR gene activation of mouse SOS Ras/Rac guanine nucleotide exchange factor 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Sos1 |
Locus ID | 20662 |
Kit Components | GA204023G1, Sos1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204023G2, Sos1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204023G3, Sos1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_009231 |
Synonyms | 4430401P03Rik; 9630010N06; AI449023 |
Summary | Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (By similarity). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (PubMed:10499589, PubMed:11524436).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN516478 | Sos1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |