Mouse Slc12a7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc12a7
Locus ID	20499
Kit Components	GA203930G1, Slc12a7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203930G2, Slc12a7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203930G3, Slc12a7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011390, NM_001360694
Synonyms	AA408796; D13Ertd261e; Kcc4
Summary	Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (By similarity). May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.[UniProtKB/Swiss-Prot Function]

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