Mouse Atxn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atxn2
Locus ID	20239
Kit Components	GA203771G1, Atxn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203771G2, Atxn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203771G3, Atxn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009125, NM_001359153
Synonyms	9630045M23Rik; ATX2; AW544490; Sca2
Summary	Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.[UniProtKB/Swiss-Prot Function]

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