Mouse Ralgds activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ralgds
Locus ID	19730
Kit Components	GA203630G1, Ralgds gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203630G2, Ralgds gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203630G3, Ralgds gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145834, NM_001145835, NM_001145836, NM_009058
Synonyms	Gnds; mKIAA1308; Rgds
Summary	Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap.[UniProtKB/Swiss-Prot Function]

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