Mouse Rad23a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rad23a
Locus ID	19358
Kit Components	GA203548G1, Rad23a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203548G2, Rad23a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203548G3, Rad23a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001297606, NM_001297607, NM_009010
Synonyms	2310040P19Rik; AL024030; HR23A; mHR23A
Summary	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome (By similarity).[UniProtKB/Swiss-Prot Function]

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