Mouse Ptpn12 activation kit by CRISPRa

CAT#: GA203474

Ptpn12 CRISPRa kit - CRISPR gene activation of mouse protein tyrosine phosphatase, non-receptor type 12



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Ptpn12
Locus ID 19248
Kit Components

GA203474G1, Ptpn12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203474G2, Ptpn12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203474G3, Ptpn12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_011203, NM_001356591, NM_001356590, NM_001356592
Synonyms P19-PTP; PTP-P19; PTP-PEST; PTPG1
Summary Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:17070019). Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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