Mouse Ptch1 activation kit by CRISPRa

CAT#: GA203442

Ptch1 CRISPRa kit - CRISPR gene activation of mouse patched 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Ptch1
Locus ID 19206
Kit Components

GA203442G1, Ptch1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203442G2, Ptch1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203442G3, Ptch1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001328514, NM_008957
Synonyms A230106A15Rik; mes; Ptc; Ptc1; Ptch
Summary Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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