Mouse Pik3r3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pik3r3
Locus ID	18710
Kit Components	GA203219G1, Pik3r3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203219G2, Pik3r3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203219G3, Pik3r3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_181585, NM_001355584, NM_001355585, NM_001355586
Synonyms	AA414954; p55pik
Summary	Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.[UniProtKB/Swiss-Prot Function]

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