Mouse P2rx1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2rx1
Locus ID	18436
Kit Components	GA203076G1, P2rx1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203076G2, P2rx1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203076G3, P2rx1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008771
Synonyms	AI323649; BB122383; P2x; Pdcd3; RP-2
Summary	Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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