Mouse Osmr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osmr
Locus ID	18414
Kit Components	GA203064G1, Osmr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203064G2, Osmr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203064G3, Osmr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001310469, NM_011019
Synonyms	OSMRB
Summary	Associates with IL31RA to form the IL31 receptor (PubMed:9920829). Binds IL31 to activate STAT3 and possibly STAT1 and STAT5 (By similarity). Capable of transducing OSM-specific signaling events (By similarity).[UniProtKB/Swiss-Prot Function]

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