Mouse Odf2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Odf2
Locus ID	18286
Kit Components	GA203007G1, Odf2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203007G2, Odf2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203007G3, Odf2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113213, NM_001113214, NM_001177659, NM_001177661, NM_001177662, NM_013615, NM_001355136, NM_001355137, NM_001355138, NM_001369060
Synonyms	AI848335; MMTEST29
Summary	Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly (By similarity).[UniProtKB/Swiss-Prot Function]

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