Mouse Ntrk3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ntrk3
Locus ID	18213
Kit Components	GA202987G1, Ntrk3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202987G2, Ntrk3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202987G3, Ntrk3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008746, NM_182809
Synonyms	AW125844; Ntrk3_tv3; TrkC
Summary	Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.[UniProtKB/Swiss-Prot Function]

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