Mouse Slc11a2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc11a2
Locus ID	18174
Kit Components	GA202962G1, Slc11a2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202962G2, Slc11a2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202962G3, Slc11a2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001146161, NM_008732, NM_001356952
Synonyms	DCT1; DMT1; mk; Nramp2; van
Summary	May serve to import iron into the mitochondria (By similarity). Important in metal transport, in particular iron. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution.[UniProtKB/Swiss-Prot Function]

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