Mouse Slc11a1 activation kit by CRISPRa

CAT#: GA202961

Slc11a1 CRISPRa kit - CRISPR gene activation of mouse solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Slc11a1
Locus ID 18173
Kit Components

GA202961G1, Slc11a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202961G2, Slc11a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202961G3, Slc11a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_013612
Synonyms Bcg; Ity; ity; Ity1; Lsh; Nramp; Nramp1
Summary Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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