Mouse Nkx2-5 activation kit by CRISPRa
CAT#: GA202910
Nkx2-5 CRISPRa kit - CRISPR gene activation of mouse NK2 homeobox 5
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Nkx2-5 |
Locus ID | 18091 |
Kit Components | GA202910G1, Nkx2-5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202910G2, Nkx2-5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202910G3, Nkx2-5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_008700 |
Synonyms | Csx; Nkx-2.5; Nkx2.5; tinman |
Summary | Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Binds to the core DNA motif of NPPA promoter. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN511024 | Nkx2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |