Mouse Nkx2-3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nkx2-3
Locus ID	18089
Kit Components	GA202909G1, Nkx2-3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202909G2, Nkx2-3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202909G3, Nkx2-3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008699
Synonyms	Nkx-2.3; Nkx2.3; tinman
Summary	Transcriptional regulator essential for normal development and functions of the small intestine and spleen. Activates directly MADCAM1 expression. Required for homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. May have a role during pharyngeal organogenesis.[UniProtKB/Swiss-Prot Function]

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