Mouse Nin activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nin
Locus ID	18080
Kit Components	GA202904G1, Nin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202904G2, Nin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202904G3, Nin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081453, NM_001286079, NM_001286080, NM_008697, NR_104397, NR_104398
Synonyms	3110068G20Rik; AI385615; AU024711; mKIAA1565
Summary	Centrosomal protein required for the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15784680, PubMed:10934040). May also act as a centrosome maturation factor (By similarity). May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15784680). Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules (By similarity). Required for centriole organization and microtubule anchoring at the mother centriole (By similarity).[UniProtKB/Swiss-Prot Function]

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