Mouse Nfya activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfya
Locus ID	18044
Kit Components	GA202892G1, Nfya gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202892G2, Nfya gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202892G3, Nfya gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001110832, NM_001347401, NM_001347402, NM_010913
Synonyms	AA407810; Cbf-b; SEZ-10; SEZ10
Summary	Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.[UniProtKB/Swiss-Prot Function]

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