Mouse Nfkbil1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfkbil1
Locus ID	18038
Kit Components	GA202888G1, Nfkbil1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202888G2, Nfkbil1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202888G3, Nfkbil1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010909, NM_001364909
Synonyms	Def-7; IKBL
Summary	Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli (By similarity).[UniProtKB/Swiss-Prot Function]

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