Mouse Nfkbia activation kit by CRISPRa
CAT#: GA202885
Nfkbia CRISPRa kit - CRISPR gene activation of mouse nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Nfkbia |
Locus ID | 18035 |
Kit Components | GA202885G1, Nfkbia gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202885G2, Nfkbia gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202885G3, Nfkbia gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_010907 |
Synonyms | AI462015; Nfkbi |
Summary | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN510946 | Nfkbia - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |